| 货号:44852-1 mg | 规格:1 mg | 目录价:¥6365 |
| 货号:44852-10 mg | 规格:10 mg | 目录价:¥31825 |
| 货号:44852-25 mg | 规格:25 mg | 目录价:¥63650 |
| 货号:44852-5 mg | 规格:5 mg | 目录价:¥17500 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Lurbinectedin
别名:
PM01183
产品描述:
A DNA alkylating agent; induces DNA DSBs, cell cycle arrest at the S phase, and apoptosis in A549 cells; cytotoxic against a panel of 24 cancer cell lines (mean GI50 = 2.7 nM); increases the levels of cGAS and phosphorylated STING, TBK1, and IRF3 in PB115, DMS 114, NCI H446, and NCI H196 cells at 10 nM; decreases tumor weight in NCI H460, A2780, HT-29, and HGC-27 mouse xenograft models at 0.18 mg/kg; decreases tumor volume in an immunocompetent genetically engineered mouse model of SCLC in combination with an anti-PD-L1 antibody
保存温度:
-20
运输温度:
-20
预期分子量:
784.881
产品形式:
A solid
纯度:
≥98%
CAS号:
497871-47-3
分子式:
C41H44N4O10S
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