深圳欣博盛生物科技有限公司 a1

LY294002 (hydrochloride)
货号:39171-1 mg 规格:1 mg 目录价:¥375
货号:39171-10 mg 规格:10 mg 目录价:¥2037
货号:39171-25 mg 规格:25 mg 目录价:¥3685
货号:39171-5 mg 规格:5 mg 目录价:¥1394
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
LY294002 (hydrochloride)
产品描述:
A multi-kinase inhibitor; inhibits CK2 (IC50 = 0.098 µM), the PI3K subunits p110α, p110β, p110δ, and p110γ (IC50s = 0.497, 0.554, 0.331, and 3.8 µM, respectively), and DNA-PK (IC50 = 6 µM), among other kinases, as well as CK1, GSK3α, and GSK3β by greater than 40% at 10 µM; inhibits LPS-induced activation of NF-κB in a reporter assay using RAW 264.7 macrophages at 20 µM; induces apoptosis and autophagy in SGC-7901 cells at 50 µM; reduces tumor volume in DLD-1 and LoVo mouse xenograft models at 2 ng/ml/kg; reduces aging-induced increases in the number of aging SA-β-gal-positive human VSMCs at 20 µM in the 5th to 15th generations
保存温度:
-20
运输温度:
-20
预期分子量:
307.34322
产品形式:
A solid
纯度:
≥98%
CAS号:
934389-88-5
分子式:
C19H17NO3 • HCl
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