| 货号:29496-10 mg | 规格:10 mg | 目录价:¥2251 |
| 货号:29496-25 mg | 规格:25 mg | 目录价:¥5253 |
| 货号:29496-5 mg | 规格:5 mg | 目录价:¥1206 |
| 货号:29496-50 mg | 规格:50 mg | 目录价:¥8750 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
LY344864 (hydrochloride)
产品描述:
A 5-HT1F receptor agonist (Ki = 6 nM); selective for 5-HT1F over 5-HT1A-E , 5-HT2A-C, and 5-HT7 receptors (Kis = 0.53-4.85 µM), as well as dopamine D1 and D2, GABAA, histamine H1, muscarinic, and α1-, α2-, and β-adrenergic receptors (Kis = 3.69->100 µM); inhibits forskolin-stimulated cAMP accumulation in L-M(TK-) cells expressing recombinant human 5-HT1F receptors (EC50 = 3 nM); decreases electrically stimulated extravasation of plasma proteins in the dura mater in a rat trigeminal nerve model of migraine headache (ID50s = 0.6 and 2.1 ng/kg for i.v. and oral administration, respectively)
保存温度:
-20
运输温度:
-20
预期分子量:
351.417403
产品形式:
A solid
纯度:
≥98%
CAS号:
1217756-94-9
分子式:
C21H22FN3O • HCl
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