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折扣/货期| 货号：14641-10 mg | 规格：10 mg | 目录价：￥1661.6 |
| 货号：14641-25 mg | 规格：25 mg | 目录价：￥2800.6 |
| 货号：14641-5 mg | 规格：5 mg | 目录价：￥884.4 |
| 货号：14641-50 mg | 规格：50 mg | 目录价：￥5185.8 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Maraviroc
别名:
UK 427857
产品描述:
A CCR5 antagonist (Ki = 0.24 nM for the rhesus monkey recombinant receptor); inhibits binding of MIP-1α, MIP-1β, and RANTES to HEK293 cell membranes expressing CCR5 (IC50s = 3.3, 7.2, and 5.2 nM, respectively) and inhibits HIV-1 binding to CCR5 via gp120 and gp160 (IC50s = 11 and 0.22 nM, respectively); selective for CCR5 over CCR1, -2, -3, -4, -7, and -8, and CXCR1 and CXCR2 in a panel of immunological assays for ligand-induced cell chemotaxis and ligand-receptor binding (IC50s = >10 µM for all); has antiviral activity against laboratory and clinical isolates of CCR5-tropic (IC50s = 0.1-1.1 nM), but not CXCR4-tropic or dual tropic (IC50s = >10 µM), HIV-1 in isolated human PBMCs; prevents infection upon exposure to HIV-1 in humanized RAG-hum mice at 62 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
513.7
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
376348-65-1
分子式:
C29H41F2N5O
促销活动
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