官网链接
折扣/货期| 货号：AG-CR1-3615-M001 | 规格：1 mg | 目录价：￥360 |
| 货号：AG-CR1-3615-M005 | 规格：5 mg | 目录价：￥720 |
| 货号：AG-CR1-3615-M010 | 规格：10 mg | 目录价：￥1080 |
| 货号：AG-CR1-3615-M050 | 规格：50 mg | 目录价：￥3720 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MCC950 . Na
别名:
MCC950; CP-456,773; CRID3; 1-(1,2,3,5,6,7-Hexahydro- s-indacen-4-yl)-3-[4-(1-hydroxy-1-methyl-ethyl)-furan-2-sulfonyl]urea
产品描述:
Potent, selective and orally available NLRP3 inflammasome inhibitor. Blocks the release of IL-1beta in macrophages primed with LPS and activated with ATP or nigericin, but it does not inhibit NLRP1, NLRC4, AIM2, TLR2 signaling or priming of NLRP3. Prevents oligomerization of ASC in cells stimulated with LPS and nigericin. Active in vivo, blocking the production of IL-1beta and enhancing survival in mouse models of multiple sclerosis and cryopyrin-associated periodic syndrome (CAPS). Also active in ex vivo samples from individuals with Muckle-Wells syndrome. Potential therapeutic agent for NLRP3-associated syndromes, including autoinflammatory and autoimmune diseases.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
426.5
产品形式:
solid
产地:
瑞士
纯度:
>97% (HPLC)
CAS号:
256373-96-3
分子式:
C20H23N2NaO5S
促销活动
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