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折扣/货期| 货号：34762-1 mg | 规格：1 mg | 目录价：￥429 |
| 货号：34762-10 mg | 规格：10 mg | 目录价：￥1675 |
| 货号：34762-25 mg | 规格：25 mg | 目录价：￥3631 |
| 货号：34762-5 mg | 规格：5 mg | 目录价：￥951 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MCC950 (sodium salt)
别名:
CP 456,773
产品描述:
An inhibitor of NLRP3 inflammasome activation; inhibits ATP-induced IL-1β release in LPS-primed mouse BMDMs (IC50 = 7.5 nM), as well as cytosolic LPS-induced IL-1β release in Pam3CSK4-primed mouse BMDMs at 0.1 and 1 µM; selective for NLRP3 over NLRC4 and AIM2 inflammasomes and does not inhibit LPS-induced NLRP3 priming in mouse BMDMs at 10 µM; reduces ox-LDL-induced increases in caspase-1 activity and inhibits pyroptosis in THP-1 macrophages at 1 µM; reduces myocardial fibrosis in mice following myocardial infarction induced by left coronary artery ligation at 10 mg/kg; improves forelimb grip strength and reduces spinal edema in a mouse model of spinal crush injury at 10 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
403.4731
产品形式:
A solid
纯度:
≥98%
CAS号:
256373-96-3
分子式:
C20H23N2O5S • Na
促销活动
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