MCL1 Antibody-多抗-深圳欣博盛生物科技有限公司

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MCL1 Antibody

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：R31553

规格：100 ug

目录价：￥6488.05

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

MCL1 Antibody

产品描述:

Myeloid cell leukemia 1 is a protein that in humans is encoded the MCL1 gene. It is a potent multidomain antiapoptotic protein of the BCL2 family that heterodimerizes with other BCL2 family members to protect against apoptotic cell death. MCL1 as an attractive candidate for regulation of hematopoietic stem cell homeostasis that is highly expressed in hematopoietic stem cells and regulated by growth factor signals. It is a critical and specific regulator essential for ensuring the homeostasis of early hematopoietic progenitors. During mitotic arrest, MCL1 protein levels decline markedly, through a posttranslational mechanism, potentiating cell death. Phosphorylation of the protein directs its interaction with the tumor suppressor protein FBW7, which is the substrate-binding component of a ubiquitin ligase complex.

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

WB, IHC-P

同种型:

Rabbit IgG

免疫原:

Human partial recombinant protein (AA 1-350) was used as the immunogen for this MCL1 antibody.

克隆性:

Polyclonal (rabbit origin)

纯化方式:

Antigen affinity

保存温度:

After reconstitution, the MCL1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

产品形式:

Antigen affinity purified

存储溶液:

0.5mg/ml if reconstituted with 0.2ml sterile DI water

产地:

美国

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