| 货号:42055-10 mg | 规格:10 mg | 目录价:¥3149 |
| 货号:42055-25 mg | 规格:25 mg | 目录价:¥6459 |
| 货号:42055-5 mg | 规格:5 mg | 目录价:¥1849 |
| 货号:42055-50 mg | 规格:50 mg | 目录价:¥10144 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
MCUF-651
产品描述:
A GC-A positive allosteric modulator; induces the production of cGMP in the presence (EC50 = 0.45 µM) but not the absence of ANP in HEK293 cells expressing human GC-A; selective for GC-A over GC-B in HEK293 cells expressing the human receptors at 10 µM; binds to the GC-A extracellular domain (Kd = 397 nM) and enhances the binding of ANP to the GC-A extracellular domain in cell-free assays; enhances ANP-induced production of cGMP in primary human renal proximal tubular cells, visceral adipocytes, and cardiomyocytes from 1-10 µM; inhibits TGF-ß1-induced hypertrophy of primary human cardiomyocytes in combination with ANP; induces cGMP production in GC-A-expressing HEK293 cells incubated with plasma isolated from patients with hypertension or heart failure
保存温度:
-20
运输温度:
-20
预期分子量:
368.445746
产品形式:
A solid
纯度:
≥98%
CAS号:
2747162-85-0
分子式:
C17H22F2N4OS
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