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MED7 Antibody

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V9748SAF-100UG

规格：100 ug

目录价：￥6652.1

产品详情

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产品名称:

MED7 Antibody

产品描述:

MED7 (Mediator of RNA polymerase II transcription subunit 7), also known as HKQ, QK, QK3 or quaking, is a 341 amino acid protein that localizes to both the cytoplasm and the nucleus and contains one KH domain. Expressed in the frontal cortex of the brain, MED7 functions as an RNA-binding protein that plays an important role in myelinization and specifically binds to the RNA core sequence 5. Additionally, MED7 regulates pre-mRNA splicing, and mRNA export and is involved in protecting and promoting the stability of select mRNAs. MED7 may be methylated by PRMT1 and may also be phosphorylated at its C-terminus, an event that decreases MED7 mRNA-binding affinity. Defects or deletions in the gene encoding MED7 are associated with astrocytic tumors and may be involved in the pathogenesis of schizophrenia. Multiple isoforms of MED7 exist due to alternative splicing events.

反应种属:

Human

宿主来源:

Mouse

实验应用:

ELISA, FACS, IF

同种型:

Mouse IgG2b

免疫原:

Recombinant full-length human protein was used as the immunogen for the MED7 antibody.

克隆性:

Monoclonal (mouse origin)