| 货号:43190-1 mg | 规格:1 mg | 目录价:¥1461 |
| 货号:43190-10 mg | 规格:10 mg | 目录价:¥5842 |
| 货号:43190-25 mg | 规格:25 mg | 目录价:¥9125 |
| 货号:43190-5 mg | 规格:5 mg | 目录价:¥4020 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
MEK Inhibitor
别名:
BIX02189
产品描述:
A MEK5 inhibitor (IC50 = 1.5 nM); selective for MEK5 over ERK5, ALK5, MEK1, and MEK2 (IC50s = 59, 580, >6,300, and >6,300 nM, respectively) and a panel of 79 other kinases at 10 µM; decreases the levels of phosphorylated ERK5 in sorbitol-stimulated HeLa cells at 1, 3, or 10 µM; inhibits TGF-β1-induced increases in N-cadherin levels, decreases in E-cadherin levels, and cell migration in a scratch assay in A549 cells at 10 µM; decreases the number of lung nodules in a A549 mouse model of lung metastasis at 20 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
426.52
产品形式:
A solid
纯度:
≥95%
CAS号:
334951-92-7
分子式:
C26H26N4O2
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