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折扣/货期| 货号：20097-1 mg | 规格：1 mg | 目录价：￥643 |
| 货号：20097-10 mg | 规格：10 mg | 目录价：￥4757 |
| 货号：20097-25 mg | 规格：25 mg | 目录价：￥9487 |
| 货号：20097-5 mg | 规格：5 mg | 目录价：￥2546 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MGCD-265
产品描述:
A c-Met and VEGFR2 inhibitor (IC50s = 0.029 and 0.01 µM, respectively); selective for c-Met and VEGFR2 over Chk1, EGFR, GSK3β, IGF-1R, IKKβ, JAK2, and JNK1 at 0.1 µM; inhibits VEGFR1, VEGFR3, Ron, Tie2, FLT3, c-Kit, Abl, and TrkA by 80-100% at 0.1 µM; binds to Smo in HEK293T cell membranes expressing the human receptor (Ki = 0.0417 µM for the wild-type receptor); inhibits Gli1-mediated transcription in a reporter assay in gefitinib-resistant HCC827 cells; inhibits HGF-induced migration of A549 cells and VEGF-induced proliferation of HUVECs (IC50s = 2 and 0.025 µM, respectively); reduces tumor growth in several mouse xenograft models, including prostate, colorectal, and gastric cancer models at 20 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
517.6
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
875337-44-3
分子式:
C26H20FN5O2S2
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