深圳欣博盛生物科技有限公司 a1

MK-7246
货号:34208-1 mg 规格:1 mg 目录价:¥882
货号:34208-10 mg 规格:10 mg 目录价:¥6174
货号:34208-25 mg 规格:25 mg 目录价:¥12124
货号:34208-5 mg 规格:5 mg 目录价:¥3528
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
MK-7246
产品描述:
A CRTH2/DP2 receptor antagonist (Ki = 2.5 nM); selective for CRTH2/DP2 over DP1, FP, IP, and TP receptors (Kis = 373, >25,100, >23,030, and 3,804 nM, respectively), as well as EP1-4 (Kis = 7,668-23,330 nM); inhibits 13,14-dihydro-15-keto-PGD2-induced inhibition of cAMP formation in HEK293 cells expressing human CRTH2/DP2 (IC50 = 3 nM); inhibits 13,14-dihydro-15-keto-PGD2-induced eosinophil shape change (IC50 = 2.2 nM) and CD11b upregulation on eosinophils and basophils in isolated human whole blood (IC50s = 6.2 and 5.4 nM, respectively); decreases antigen-induced late-phase bronchoconstriction and completely prevents airway hyperresponsiveness in sheep at 1 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
416.466923
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
1218918-62-7
分子式:
C21H21FN2O4S
在线留言
咨询类型
联系人
*
联系方式
*
单位名称
*
咨询内容
*
复制QQ号成功,请打开QQ后添加好友进行咨询