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折扣/货期| 货号：34208-1 mg | 规格：1 mg | 目录价：￥938 |
| 货号：34208-10 mg | 规格：10 mg | 目录价：￥6512 |
| 货号：34208-25 mg | 规格：25 mg | 目录价：￥12770 |
| 货号：34208-5 mg | 规格：5 mg | 目录价：￥3725 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MK-7246
产品描述:
A CRTH2/DP2 receptor antagonist (Ki = 2.5 nM); selective for CRTH2/DP2 over DP1, FP, IP, and TP receptors (Kis = 373, >25,100, >23,030, and 3,804 nM, respectively), as well as EP1-4 (Kis = 7,668-23,330 nM); inhibits 13,14-dihydro-15-keto-PGD2-induced inhibition of cAMP formation in HEK293 cells expressing human CRTH2/DP2 (IC50 = 3 nM); inhibits 13,14-dihydro-15-keto-PGD2-induced eosinophil shape change (IC50 = 2.2 nM) and CD11b upregulation on eosinophils and basophils in isolated human whole blood (IC50s = 6.2 and 5.4 nM, respectively); decreases antigen-induced late-phase bronchoconstriction and completely prevents airway hyperresponsiveness in sheep at 1 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
416.466923
产品形式:
A solid
纯度:
≥98%
CAS号:
1218918-62-7
分子式:
C21H21FN2O4S
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