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折扣/货期| 货号：20455-1 mg | 规格：1 mg | 目录价：￥415 |
| 货号：20455-10 mg | 规格：10 mg | 目录价：￥1246 |
| 货号：20455-25 mg | 规格：25 mg | 目录价：￥2586 |
| 货号：20455-5 mg | 规格：5 mg | 目录价：￥724 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
ML-162
别名:
CID 3689413
产品描述:
A GPX4 and TrxR1 inhibitor; covalently binds to the GPX4 active site residue Sec46 and allosteric site residue Cys66 but does not inhibit recombinant human GPX4 activity in a cell-free assay; inhibits TrxR1 in a cell-free assay (IC50 = 19.5 µM); inhibits TrxR1 in A549 cells at 0.5-15 µM; decreases GPX4 levels in MDA-MB-231 breast cancer cells; reduces the viability of BT-549 breast cancer cells, an effect that can be enhanced by α-eleostearic acid; induces Ras-synthetic lethality in mutant RAS oncogene-expressing cells (IC50s = 25 and 578 nM for HRASG12V-expressing and wild-type RAS-expressing BJeH cells, respectively)
保存温度:
-20
运输温度:
-20
预期分子量:
477.4
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
1035072-16-2
分子式:
C23H22Cl2N2O3S
促销活动
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