| 货号:27313-10 mg | 规格:10 mg | 目录价:¥1608 |
| 货号:27313-25 mg | 规格:25 mg | 目录价:¥3752 |
| 货号:27313-5 mg | 规格:5 mg | 目录价:¥965 |
| 货号:27313-50 mg | 规格:50 mg | 目录价:¥7008 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
ML-221
产品描述:
An APJ receptor antagonist (IC50 = 4.8 μM); selective for APJ over AT1 (IC50 = >78 μM); antagonizes apelin 13-induced activation of APJ in cAMP and β-arrestin recruitment assays (IC50s = 0.7 and 1.75 μM, respectively); inhibits proliferation and angiogenesis in Mz-ChA-1 cholangiocarcinoma cells from 5-15 μM; reduces tumor growth in a Mz-ChA-1 mouse xenograft model at 150 μg/kg; reduces sciatic CCI-induced mechanical allodynia and heat hyperalgesia in rats at 10 μg/animal; inhibits pathological angiogenesis and enhances normal vessel recovery in retinal ischemic regions in a mouse model of oxygen-induced retinopathy
保存温度:
-20
运输温度:
-20
预期分子量:
385.35186
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
877636-42-5
分子式:
C17H11N3O6S
促销活动
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