| 货号:36582-10 mg | 规格:10 mg | 目录价:¥2104 |
| 货号:36582-25 mg | 规格:25 mg | 目录价:¥4958 |
| 货号:36582-5 mg | 规格:5 mg | 目录价:¥1112 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
ML-417
产品描述:
A dopamine D3 receptor agonist; selective for dopamine D3 over dopamine D2 receptors (EC50s = 38 and >10,000 nM, respectively, in β-arrestin recruitment assays using CHO-K1 cells expressing the human receptors), dopamine D1, D4, and D5 receptors, and a panel of 45 GPCRs, transporters, and ion channels at 10 µM; inhibits forskolin-induced cAMP accumulation in HEK293 cells expressing the human dopamine D3 receptor (IC50 = 86 nM); induces phosphorylation of ERK in CHO-K1 cells expressing the human dopamine D3 receptor (EC50 = 21 nM); protects against 6-OHDA-induced cell death in human iPSC-derived cells differentiated into dopaminergic neurons at 50 nM
保存温度:
-20
运输温度:
-20
预期分子量:
379.45232
产品形式:
A solid
纯度:
≥98%
CAS号:
1386162-69-1
分子式:
C22H25N3O3
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