Mouse Plasma Cell Depletion Starter Set-抗体对-深圳欣博盛生物科技有限公司

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Mouse Plasma Cell Depletion Starter Set

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-44B-0020-KI01

规格：1 Set

目录价：￥7560

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Mouse Plasma Cell Depletion Starter Set

产品描述:

The Mouse Plasma Cell Depletion Starter Set contains two blocking antibodies, APRIL (mouse), mAb (blocking) (Centotto-1) and BAFF (mouse), mAb (blocking) (Sandy-2), that are sufficient, when used together, to deplete the plasma cells in mouse and to phenocopy APRIL-ko and BAFF-ko mice. This starter set contains enough reagents to deplete plasma cells in 2-3 mice. APRIL (A proliferation-inducing ligand, TNFSF13) / BAFF (B-cell-activating factor, TNFSF13B) axis is required and nonredundant to maintaining all IgA, and IgM antibody-secreting plasma cells and most of IgG antibody-secreting plasma cells in the bone marrow, spleen, gut and serum. APRIL and BAFF rely mainly on three ligand/receptor pairs: APRIL-BCMA, BAFF-TACI, and APRIL-TACI.

靶标/特异性:

Both antibodies in the Mouse Plasma Cell Depletion Starter Set have been thoroughly validated in mice. Antibodies against APRIL (Centotto-1) and BAFF (Sandy-2) are injected in C57BL/6J at 2mg/kg (about 20-40µg/mouse) intraperitoneal (i.p.) once a week. For details see reference M. Eslami, et al.; PNAS 21, e2404309121 (2024).

同种型:

Mouse IgG1

产品浓度:

1mg/ml

保存温度:

+4°C

运输温度:

产品形式:

liquid

产地:

瑞士

内毒素水平: