| 货号:21903-1 mg | 规格:1 mg | 目录价:¥496 |
| 货号:21903-10 mg | 规格:10 mg | 目录价:¥2600 |
| 货号:21903-25 mg | 规格:25 mg | 目录价:¥5842 |
| 货号:21903-5 mg | 规格:5 mg | 目录价:¥1420 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
MP-A08
别名:
NSC 122314
产品描述:
An inhibitor of SPHK1 and SPHK2 (Kis = 27 and 6.9 μM, respectively); selective for SPHK1/2 over a panel of 140 human protein kinases at concentrations up to 25 μM; reduces generation of cellular S1P without inducing SPHK1 degradation in Jurkat cells; induces a 3.7-, 3.5-, and 5.8-fold increase in C-18 ceramide, C-20 ceramide, and C20:1-ceramide levels, respectively; reduces proliferation of a variety of human cancer cell lines (EC50s = 8-44.9 μM); reduces tumor vasculature and volume as well as S1P protein levels in A549 human lung adenocarcinoma xenografts in mice
保存温度:
-20
运输温度:
-20
预期分子量:
519.6
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
219832-49-2
分子式:
C27H25N3O4S2
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