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折扣/货期| 货号：SBB-DE0129-C050 | 规格：50 ug | 目录价：￥3836 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Mpro [3CLpro] (SARS-CoV-2) (rec.) (His)
别名:
Chymotrypsin Like Protease; SARS Coronavirus Main Proteinase
产品描述:
3CLpro recognizes the peptide sequence LQ[S/A/G] where it cleaves c-terminal to the amino acid glutamine (use product SBB-PS0130, KTSAVLQ-Rh110-Glu as universal substrate). The protease 3CLpro is a potential drug target for coronavirus infections due to its essential role in processing the polyproteins that are translated from the viral RNA. The X-ray structures of the unliganded SARS-CoV-2 protease 3CLpro and its complex with an alpha-ketoamide inhibitor provides a basis for design of alpha-ketoamide inhibitors. This SARS Coronavirus recombinant 3CLpro is N-terminally His10-tagged and expressed in E.coli.
宿主来源:
E. coli
产品浓度:
Lot dependent.
保存温度:
-80°C
运输温度:
Dry Ice
预期分子量:
~36kDa
产品形式:
liquid
存储溶液:
Liquid. In 50mM HEPES pH 7.5, 100mM NaCl, 1mM TCEP.
产地:
瑞士
纯度:
>98% (SDS-PAGE)
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