深圳欣博盛生物科技有限公司 a1

MPT0G211
货号:43666-1 mg 规格:1 mg 目录价:¥871
货号:43666-10 mg 规格:10 mg 目录价:¥6968
货号:43666-25 mg 规格:25 mg 目录价:¥10880.8
货号:43666-5 mg 规格:5 mg 目录价:¥4127.2
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
MPT0G211
产品描述:
An HDAC6 inhibitor (IC50 = 0.291 nM). It is selective for HDAC6 over HDAC1-5 (IC50s = 9.55, 12.5, 7.75, 4.438, and 3.112 µM, respectively), HDAC7-11 (IC50s = 0.709, 1.19, 1.53, 9.791, and 0.376 µM, respectively), sirtuin 1 (SIRT1; IC50 = > 20 µM), and a panel of 97 kinases at 1 µM; inhibits the growth of RPMI-8226, U266, and NCI H929 cells (GI50s = 7.49, 40.61, and 9.14 µM, respectively); does not inhibit the growth of HS-5 normal bone marrow cells (GI50 = >100 µM); reduces tumor volume in an RPMI-8226 mouse xenograft model at 30 mg/kg; decreases cognitive deficits and tau phosphorylation in the 3xTg mouse model of Alzheimer's disease
保存温度:
-20
运输温度:
-20
预期分子量:
293.326
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
2151853-97-1
分子式:
C17H15N3O2
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