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折扣/货期| 货号：36563-1 mg | 规格：1 mg | 目录价：￥2559 |
| 货号：36563-10 mg | 规格：10 mg | 目录价：￥15303 |
| 货号：36563-5 mg | 规格：5 mg | 目录价：￥12127 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MRTX-1719
别名:
(M)-27|BMS-986504|Navlimetostat
产品描述:
An inhibitor of the PRMT5/MTA complex; selectively binds to the PRMT5/MTA complex over the PRMT5/SAM complex (Kds = 0.14 and 9.4 pM, respectively); selectively decreases protein dimethylarginine methylation levels in MTAP-/- HCT116 cells (IC50 = 8 nM) over wild-type HCT116 cells (IC50 = 653 nM), as well as selectively reduces the viability of MTAP-/- HCT116 cells (IC50 = 12 nM) over wild-type HCT116 cells (IC50 = 890 nM); reduces tumor volume in an MTAP-/- Lu-99 lung cancer mouse xenograft model at 12.5 to 100 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
464.879363
产品形式:
A solid
纯度:
≥95%
CAS号:
2630904-45-7
分子式:
C23H18ClFN6O2
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