深圳欣博盛生物科技有限公司 a1

MS1943
货号:35466-1 mg 规格:1 mg 目录价:¥482
货号:35466-10 mg 规格:10 mg 目录价:¥2358
货号:35466-25 mg 规格:25 mg 目录价:¥4717
货号:35466-5 mg 规格:5 mg 目录价:¥1420
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
MS1943
产品描述:
A PROTAC that drives EZH2 degradation; inhibits EZH2 (IC50 = 120 nM) and is selective for EZH2 over EZH1, as well as a panel of 45 kinases at 10 µM; induces EZH2 degradation and reduces H3K27me3, as well as induces activation of the unfolded protein response pathway in MDA-MB-468 TNBC cells at 4 µM; inhibits the growth of MDA-MB-468 cells in vitro (GI50 = 2.2 µM); reduces tumor volume in an MDA-MB-468 mouse xenograft model at 50 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
718.93028
产品形式:
A solid
纯度:
≥98%
CAS号:
2225938-17-8
分子式:
C42H54N8O3
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