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折扣/货期| 货号：30140-1 mg | 规格：1 mg | 目录价：￥482 |
| 货号：30140-10 mg | 规格：10 mg | 目录价：￥2265 |
| 货号：30140-5 mg | 规格：5 mg | 目录价：￥1474 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MSA-2
别名:
5,6-dimethoxy-γ-oxo-benzo[b]thiophene-2-Butanoic Acid
产品描述:
A STING agonist; binds to wild-type and HAQ variant STING in a 3H-cGAMP filtration binding assay (EC50s = 2.48 and 1.72 μM, respectively); induces secretion of IFN-β from THP-1 cells by 129% relative to induction by 2’3’-cGAMP at 30 μM; reduces tumor growth in an MC-38 syngeneic mouse model of colon carcinoma in a dose-dependent manner and induces tumor regression at 450 μg, intratumorally, and 50 mg/kg, s.c.; acts synergistically with an anti-PD-1 antibody in MC-38, CT26, B16/F10, and LL/2 syngeneic mouse models
保存温度:
-20
运输温度:
-20
预期分子量:
294.32396
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
129425-81-6
分子式:
C14H14O5S
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