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折扣/货期| 货号：10007853 | 规格：1 mg | 目录价：￥4774 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Muraglitazar
别名:
BMS-298585
产品描述:
A dual agonist of PPARα and PPARγ (EC50s = 0.32 and 0.11 μM, respectively); selective for PPARα/γ over other nuclear receptors, including PPARδ, RXRα, RARs, ERα/β, AR, and PR; reduces the size of lipid droplets in oleic acid-treated HepaRG human hepatocytes at 50 μM; reduces plasma levels of glucose, triglycerides, free fatty acids, and insulin by 54, 33, 62, and 48%, respectively, in db/db mice at 10 mg/kg per day; reduces plasma levels of glucose, triglycerides, and cholesterol in diet-induced obese mice at 10 mg/kg per day; inhibits LPS-induced increases in NO production and IL-6, TNF-α, and iNOS protein levels in J774 murine macrophages; inhibits carrageenan-induced paw edema in mice at 12.5-50 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
516.5
产品形式:
A crystalline powder
有效期:
1460
纯度:
≥90%
CAS号:
331741-94-7
分子式:
C29H28N2O7
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