| 货号:RQ5667 | 规格:100 ug | 目录价:¥6488.05 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Muscleblind-like 1 Antibody / MBNL1
产品描述:
Muscleblind-like (Drosophila), also known as MBNL1, is a protein that in humans is encoded by the MBNL1 gene. It is mapped to 3q25.1-q25.2. This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities.
反应种属:
Human, Mouse, Rat, Monkey
宿主来源:
Rabbit
实验应用:
WB, IHC-P, IF, Direct ELISA
同种型:
Rabbit IgG
免疫原:
Recombinant human protein (amino acids Q89-M388) was used as the immunogen for the Muscleblind-like 1 antibody.
克隆性:
Polyclonal
纯化方式:
Affinity purified
保存温度:
After reconstitution, the Muscleblind-like 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
产品形式:
Antigen affinity purified
存储溶液:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
产地:
美国
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