MX1 Antibody / Myxovirus resistance protein 1 / MxA-抗病毒抗体-深圳欣博盛生物科技有限公司

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MX1 Antibody / Myxovirus resistance protein 1 / MxA

品牌：NSJ Bio

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说明书

折扣/货期

货号：V4843-100UG	规格：100 ug	目录价：￥6652.1
货号：V4843-20UG	规格：20 ug	目录价：￥3082.1

产品详情

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产品名称:

MX1 Antibody / Myxovirus resistance protein 1 / MxA

产品描述:

The Dynamin family of microtubule-associated proteins function as GTPases that are involved in microtubule bundling and endocytosis. In mice, Mx2 (myxovirus resistance protein 2) and Mx1 (myxovirus resistance protein 1) are members of the Dynamin family that are involved in the immune response to viral infections. Localized to the cytoplasm, Mx2 contains one GED domain and is expressed in response to viral infection or treatment by IFN-a/IFN-b. Once expression is induced, Mx2 accumulates in the cytoplasm and inhibits the replication of vesicular stomatitis virus (VSV), thereby conferring resistance to VSV infection. Unlike Mx2, Mx1 is localized to the nucleus where, upon induction by IFN-a/IFN-b, it provides selective resistance to infection by the highly lethal H5N1 influenza virus. In humans, MxA and MxB function in a similar manner to Mx1 and Mx2, conferring resistance to specific target viruses. Mx3 is a rat-specific member of the myxovirus resistance protein family.

反应种属:

Human

宿主来源:

Mouse

实验应用:

IHC-P

同种型:

Mouse IgG2, kappa

免疫原:

A recombinant partial protein sequence (within amino acids 400-592) from the human protein was used as the immunogen for the MX1 antibody.

克隆性:

Monoclonal (mouse origin)