深圳欣博盛生物科技有限公司 a1

N6F11
货号:39919-10 mg 规格:10 mg 目录价:¥884
货号:39919-25 mg 规格:25 mg 目录价:¥1822
货号:39919-5 mg 规格:5 mg 目录价:¥523
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
N6F11
产品描述:
A ferroptosis inducer; increases the thermal stability of TRIM25 in a CETSA using PANC-1 cells at 10 µM; enhances TRIM25-dependent ubiquitination of GPX4 in a cell-free assay at 0.1 and 1 µM; induces lipid peroxidation and ferroptosis, as well as degradation of GPX4, an effect that can be reversed by carfilzomib or bortezomib, in PANC-1 cells at 5 µM; selectively induces cytotoxicity in HT-1080, PANC-1, MiaPaCa-2, and Calu-1 cancer cells over neutrophils, dendritic cells, NK cells, and CD8+ T cells; decreases tumor volume in a KPC murine PDAC model at 10 mg/kg, which can be inhibited by liproxstatin-1 or an anti-CD8 antibody
保存温度:
-20
运输温度:
-20
预期分子量:
313.20278
产品形式:
A solid
纯度:
≥95%
CAS号:
851398-76-0
分子式:
C13H10Cl2N2OS
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