深圳欣博盛生物科技有限公司 a1

Naloxegol (oxalate)
货号:23731-10 mg 规格:10 mg 目录价:¥4703
货号:23731-25 mg 规格:25 mg 目录价:¥8455
货号:23731-5 mg 规格:5 mg 目录价:¥2626
货号:23731-50 mg 规格:50 mg 目录价:¥13789
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Naloxegol (oxalate)
别名:
AZ 13337019|NKTR-118
产品描述:
A peripherally acting antagonist of the μ-opioid receptor (Ki = 7.42 nM; pA2 = 7.95); selective for the μ-opioid receptor over the δ-opioid receptor (Ki = 866 nM); acts as a partial agonist of κ-opioid receptors in vitro (EC50 = 47 nM for [35S]GTPγS binding); reverses morphine-induced decreases in gastrointestinal motility and analgesia in a hot-plate assay in rats (ED50s = 23.1 and 55.4 mg/kg, respectively); exhibits minimal brain uptake in a rat brain perfusion model
保存温度:
-20
运输温度:
-20
预期分子量:
741.8
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1354744-91-4
分子式:
C34H53NO11 • C2H2O4
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