Nampt (Visfatin/PBEF) (human) (rec.) (His) (BULK)-其他重组蛋白-深圳欣博盛生物科技有限公司

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Nampt (Visfatin/PBEF) (human) (rec.) (His) (BULK)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-40A-0018AA-C500

规格：500 ug

目录价：￥30000

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Nampt (Visfatin/PBEF) (human) (rec.) (His) (BULK)

别名:

Pre-B Cell Colony Enhancing Factor 1; PBEF1; Nicotinamide Phosphoribosyltransferase

产品描述:

Nicotinamide phosphoribosyltransferase (Nampt; pre-B cell colony-enhancing factor; PBEF; Visfatin) is an 52kDa adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity. Recently NAMPT extracellular (eNAMPT) has been shown to be secreted from macrophages in muscles and to triggers a proliferative signal of muscle stem cell (MusC) by binding to CCR5 located at the surface receptor of MusC.

宿主来源:

E. coli

保存温度:

+4°C

运输温度:

预期分子量:

~52kDa (SDS-PAGE)

产品形式:

solid

存储溶液:

Lyophilized.

产地: