NAPRTase (human) (rec.) (His)-其他酶-深圳欣博盛生物科技有限公司

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NAPRTase (human) (rec.) (His)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-40T-0105-C050

规格：50 ug

目录价：￥4680

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

NAPRTase (human) (rec.) (His)

别名:

Nicotinate Phosphoribosyltransferase; FHA-HIT-interacting Protein; FHIP; EC 2.4.2.11

产品描述:

Human nicotinate phosphoribosyltransferase (NAPRTase) is localized in the cytoplasm and is involved in biological processes such as NAD biosynthetic and metabolic processes, nicotinamide metabolic process, nicotinate nucleotide salvage, response to oxidative stress and water-soluble vitamin metabolic process. It functions by catalyzing the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN) and is essential for NA to increase cellular NAD levels and prevent oxidative stress of the cells. It is a crucial factor in the NAD+ biosynthesis pathway. Catalytic activity: Beta-nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate.

宿主来源:

E. coli

产品浓度:

0.5mg/ml (Lot specific)

保存温度:

-20°C

运输温度:

预期分子量:

~58.0kDa

产品形式:

liquid

存储溶液:

Liquid. In 50mM HEPES/KOH pH 7.5 containing 300mM potassium chloride and 10mM DTT.

产地:

瑞士

纯度:

>98% (SDS-PAGE)

生物活性:

0.043µmol/min/mg: hNAPRTase activity was measured by a custom coupled enzymatic assay which uses a secondary enzyme for the quantification of the PRPP consumed by hNAPRTase. The reaction buffer contained 50 mM Hepes pH 7.5, 500 µM PRPP, 100 µM nicotinic acid, 20 mM MgCl2, 2.5 mM DTT and hNAPRTase at 5 µM, 25°C, spectrophotometrical monitoring.

内毒素水平:

N/A

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