官网链接
折扣/货期| 货号：28442-1 mg | 规格：1 mg | 目录价：￥670 |
| 货号：28442-10 mg | 规格：10 mg | 目录价：￥3658 |
| 货号：28442-5 mg | 规格：5 mg | 目录价：￥2157 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
NBI 74330
产品描述:
A CXCR3 antagonist (Ki = 3.6 nM in a radioligand binding assay); inhibits CXCL10- or CXCL11-induced calcium mobilization in RBL cells expressing human CXCR3 (IC50 = 7 nM for both); inhibits CXCL11-induced chemotaxis of CXCR3-expressing H9 cells and PHA/IL-2 T cells (IC50s = 3.9 and 6.6 nM, respectively); reduces peritoneal lymphocyte migration in a mouse model of peritonitis at 100 mg/kg; reduces the size and number of aortic arch atherosclerotic lesions in Ldlr-/- mice; reduces spinal cord microglial activation and levels of CXCL4, CXCL9, and CXCL10 and decreases thermal and mechanical hyperalgesia in a rat model of chronic constriction injury-induced neuropathic pain
保存温度:
-20
运输温度:
-20
预期分子量:
605.582292
产品形式:
A solid
纯度:
≥98%
CAS号:
855527-92-3
分子式:
C32H27F4N5O3
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