深圳欣博盛生物科技有限公司 a1

NDMC101
货号:20468-1 mg 规格:1 mg 目录价:¥911
货号:20468-10 mg 规格:10 mg 目录价:¥4904
货号:20468-25 mg 规格:25 mg 目录价:¥11109
货号:20468-5 mg 规格:5 mg 目录价:¥3337
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
NDMC101
产品描述:
A derivative of salicylanilide with anti-inflammatory activities; inhibits RANKL-induced osteoclast differentiation of BMDMs and RAW 264.7 cells at 10 and 15 µM; decreases RANKL-induced expression of the osteoclastogenic genes Nfatc1, Acp5, Ctsk, Oscar, Itgb3, and Dcstamp in BMDMs and inhibits phosphorylation of IĸB and nuclear translocation of NF-ĸB in RANKL-stimulated RAW 264.7 cells at 15 µM; reduces collagen-induced increases in the serum levels of TNF-α and IL-1β, as well as the numbers of osteoclasts and histological severity of bone erosion, cartilage damage, and synovial inflammation in joints in a mouse model of arthritis at 62.5 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
265.7
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1308631-40-4
分子式:
C13H9ClFNO2
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