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折扣/货期| 货号：60-532 | 规格：400 ul | 目录价：￥8687.25 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
NDUFV1 Antibody
别名:
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial, Complex I-51kD, CI-51kD, NADH dehydrogenase flavoprotein 1, NADH-ubiquinone oxidoreductase 51 kDa subunit, NDUFV1, UQOR1
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB
同种型:
Rabbit Ig
克隆性:
Polyclonal
纯化方式:
This antibody is purified through a protein A column, followed by peptide affinity purification.
偶联:
Unconjugated
产品浓度:
batch dependent
保存温度:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
Supplied in PBS with 0.09% (W/V) sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
The mitochondrial respiratory chain provides energy to
cells via oxidative phosphorylation and consists of four
membrane-bound electron-transporting protein complexes (I-IV) and
an ATP synthase (complex V). This gene encodes a 51 kDa subunit of
the NADH:ubiquinone oxidoreductase complex I; a large complex with
at least 45 nuclear and mitochondrial encoded subunits that
liberates electrons from NADH and channels them to ubiquinone. This
subunit carries the NADH-binding site as well as flavin
mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I
are a common cause of mitochondrial dysfunction; a syndrome that
occurs in approximately 1 in 10,000 live births. Mitochondrial
complex I deficiency is linked to myopathies, encephalomyopathies,
and neurodegenerative disorders such as Parkinson's disease and
Leigh syndrome. Alternative splicing results in multiple transcript
variants encoding distinct isoforms.
Accession #:
P49821
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