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折扣/货期| 货号：40647-10 mg | 规格：10 mg | 目录价：￥3511 |
| 货号：40647-100 mg | 规格：100 mg | 目录价：￥16589 |
| 货号：40647-5 mg | 规格：5 mg | 目录价：￥1849 |
| 货号：40647-50 mg | 规格：50 mg | 目录价：￥10144 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
NE52-QQ57
产品描述:
A GPR4 antagonist (IC50 = 0.04 µM); selective for GPR4 over hERG and histamine H3 receptor (IC50s = 19 and >30 µM, respectively); decreases the IL-33-induced increases in IL-17, IFN-γ, TNF-α, NF-κB, MMP-2, MMP-9, and COX-2 levels in, and PGE2 secretion by, HMC-1 mast cells at 2 µM; reduces IL-33-induced increases in mitochondrial ROS in the same cells; increases colon length and reduces fecal blood levels and incidence of diarrhea, lymph node volumes and spleen weight, as well as reduces distal and mid colon inflammation and leukocyte infiltration levels, in a mouse model of DSS-induced ulcerative colitis at 30 mg/kg twice per day; increases the mechanical paw withdrawal threshold in a rat model of CFA-induced inflammatory pain at 3, 10, or 30 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
416.51896
产品形式:
A solid
纯度:
≥98%
CAS号:
1401728-56-0
分子式:
C24H28N6O
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