NEK2 Antibody-多抗-深圳欣博盛生物科技有限公司

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NEK2 Antibody

品牌：NSJ Bio

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说明书

折扣/货期

货号：F40172-0.08ML	规格：0.08 ml	目录价：￥2962.25
货号：F40172-0.4ML	规格：0.4 ml	目录价：￥6343.55

产品详情

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产品名称:

NEK2 Antibody

产品描述:

NEK2 is closely related in its catalytic domain to the serine/threonine protein kinase NIMA of Aspergillus nidulans which is required for entry into mitosis and may function in parallel to the universal mitotic inducer p34cdc2. Like NIMA, the Nek2 protein is almost undetectable during G1 but accumulates progressively throughout S, reaching maximal levels in late G2. These observations demonstrate that NEK2 resembles Aspergillus NIMA, both in its catalytic domain, and cell cycle-dependent expression. Recombinant NEK2 is active as a serine/threonine-specific protein kinase and may undergo autophosphorylation. Both human NEK2 and fungal NIMA phosphorylate a similar, but not identical, set of proteins and synthetic peptides. NEK2 is shown to be expressed most abundantly in adult testis and there is increasing evidence that NEK2 is abnormally expressed in a wide variety of human cancers. This antibody is specific to isoform 2 of NEK2.

反应种属:

Human

宿主来源:

Rabbit

实验应用:

WB, ELISA

同种型:

Rabbit Ig

免疫原:

A portion of amino acids 350-382 from the human protein was used as the immunogen for this NEK2 antibody.

克隆性:

Polyclonal (rabbit origin)