Nelfinavir . mesylate-抑制剂-深圳欣博盛生物科技有限公司

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Nelfinavir . mesylate

品牌：Adipogen

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说明书

折扣/货期

货号：AG-CR1-3726-M010	规格：10 mg	目录价：￥600
货号：AG-CR1-3726-M050	规格：50 mg	目录价：￥2400

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Nelfinavir . mesylate

别名:

AG-1343; Nelfin; Viracept

产品描述:

Nelfinavir is an orally bioavailable competitive inhibitor of the human immunodeficiency virus. It potently inhibits HIV-1 (Ki=2nM) and HIV-2 protease in vitro. HIV-1 protease is important for the replication of the virus within the cell and the release of mature viral particles from the infected cell. Formulations containing nelfinavir have been used in combination with HIV reverse transcriptase inhibitors for the treatment of AIDS. Nelfinavir shows other antimicrobial and antiviral activity. It inhibits maturation and export of the Herpes Simplex 1 virus and the Kaposi's Sarcoma virus, replication of SARS-CoV and also replication of SARS-CoV-2, cause for the epidemic COVID-19. Has potent anti-cancer activity against a broad selection fo cancer cell types. Shown to induce apoptosis, autophagy, cell cycle arrest and endoplasmic reticulum stress, which consequently leads to cancer cell death. Shown to inhibit the Akt/PKB signaling pathway. It acts as an antifibrotic agent and is used to treat pulmonary fibrosis in patients with systemic sclerosis (SSc) and reduces inflammation by activating protein phosphatase 2 (PP-2) and blocking mitogen-activated protein kinases (MAPK) signaling in macrophages. It has also shown pan-proteasome inhibition in AMO-1 and U266 myeloma cells.

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

567.8 . 96.1

产品形式:

solid

产地:

瑞士

纯度:

>98% (HPLC)