深圳欣博盛生物科技有限公司 a1

NEO2734
货号:41030-10 mg 规格:10 mg 目录价:¥6981
货号:41030-100 mg 规格:100 mg 目录价:¥36703
货号:41030-5 mg 规格:5 mg 目录价:¥3672
货号:41030-50 mg 规格:50 mg 目录价:¥23865
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
NEO2734
产品描述:
A dual inhibitor of BET bromodomains and p300/CBP; binds to BRD2, BRD3, and BRD4 (Kds = 3.2, 2.3, and 6.5 nM, respectively), BRDT1 and BRDT2 (Kds = 3.1 and 25 nM, respectively), and p300 and CBP (Kds = 25 and 23 nM, respectively); inhibits the growth of DU145 prostate cancer cells (IC50 = 1.08 µM) and DU145 cells containing SPOPQ165P (IC50 = 0.69 µM); reduces tumor growth, as well as intratumoral levels of PSA, in prostate cancer PDX mouse models expressing either wild-type SPOP or SPOPQ165P at 30 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
435.439589
产品形式:
A solid
纯度:
≥98%
CAS号:
2081072-29-7
分子式:
C22H24F3N3O3
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