Nepicastat (hydrochloride)-抑制剂-深圳欣博盛生物科技有限公司

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Nepicastat (hydrochloride)

品牌：Cayman

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说明书

折扣/货期

货号：22126-1 mg	规格：1 mg	目录价：￥496
货号：22126-10 mg	规格：10 mg	目录价：￥2600
货号：22126-25 mg	规格：25 mg	目录价：￥5842
货号：22126-5 mg	规格：5 mg	目录价：￥1420

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Nepicastat (hydrochloride)

别名:

RS 25560-197

产品描述:

An inhibitor of DBH (IC50 = 9 nM for the purified human enzyme); selective for DBH over a panel of 12 enzymes and 13 neurotransmitter receptors (IC50s or Kis = >10 μM); dose-dependently reduces norepinephrine content and increases dopamine content in the mesenteric artery, left ventricle, and cerebral cortex in spontaneously hypertensive rats, as well as in the renal artery, left ventricle, and cerebral cortex in beagle dogs; attenuates increases in diastolic blood pressure and heart rate induced by preganglionic sympathetic nerve stimulation in pithed spontaneously hypertensive rats at 10 and 30 mg/kg; reduces the progressive ratio response for cocaine, but not food or sucrose pellets, in rats at 50 mg/kg; reduces reinstatement of cocaine-seeking behavior induced by cues, yohimbine, or foot-shock in rats

保存温度:

-20

运输温度:

-20

预期分子量:

295.34

产品形式:

A crystalline solid

纯度:

≥98%

CAS号:

170151-24-3