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折扣/货期| 货号：43142-1 mg | 规格：1 mg | 目录价：￥392 |
| 货号：43142-10 mg | 规格：10 mg | 目录价：￥2940 |
| 货号：43142-25 mg | 规格：25 mg | 目录价：￥6370 |
| 货号：43142-5 mg | 规格：5 mg | 目录价：￥1764 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
NF 1819
别名:
NSD1819
产品描述:
A MAGL inhibitor (IC50s = 0.25 and 7.4 nM for the rat and human enzymes, respectively); selective for MAGL over FAAH (IC50 = 2,880 nM for the human enzyme) and CB1 and CB2 receptors (IC50s = >10,000 nM for both); decreases disease severity in a mouse model of MOG (35-55)-induced EAE at 3 mg/kg, an effect that can be reversed by AM251 or AM630; induces analgesia in the formalin test in mice at 0.3 mg/kg; inhibits LPS-induced motor and cognitive impairments in the rotarod and passive avoidance tests, respectively, and LPS-induced depressive-like behavior in the forced swim test, in mice at 3 mg/kg; increases the number of entries into and percentage of time spent in the open arms of the elevated plus maze in mice, indicating anxiolytic-like activity, in a rat model of predator stress-induced anxiety using TMT
保存温度:
-20
运输温度:
-20
预期分子量:
463.469403
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
1881244-28-5
分子式:
C24H22FN5O4
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