官网链接
折扣/货期| 货号：36628-1 g | 规格：1 g | 目录价：￥2412 |
| 货号：36628-250 mg | 规格：250 mg | 目录价：￥764 |
| 货号：36628-5 g | 规格：5 g | 目录价：￥7450 |
| 货号：36628-500 mg | 规格：500 mg | 目录价：￥1434 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Nilotinib (hydrochloride hydrate)
产品描述:
An inhibitor of wild-type and mutant Bcr-Abl (IC50s = 15 and 9-400 nM, respectively); selective for wild-type and mutant Bcr-Abl over Src and LYN (IC50s = >5,000 nM for both); inhibits Bcr-Abl autophosphorylation and cell proliferation in Ba/F3 cells expressing wild-type or mutant Bcr-Abl (IC50s = 7-155 and 13-51 nM, respectively); reduces midbrain Bcr-Abl autophosphorylation, amyloid-β levels, and neuronal loss, as well as improves autophagosome clearance and reverses cognitive deficits in the Tg2576 transgenic mouse model of Alzheimer’s disease at 1 mg/kg; reduces serum creatine levels, renal profibrotic gene expression, and tubulointerstitial damage, as well as increases survival in a rat model of 5/6 nephrectomy-induced chronic kidney disease
保存温度:
-20
运输温度:
-20
预期分子量:
529.516069
产品形式:
A solid
纯度:
≥98%
CAS号:
923288-90-8
分子式:
C28H22F3N7O • HCl [H2O]
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询