| 货号:21509-1 mg | 规格:1 mg | 目录价:¥549 |
| 货号:21509-10 mg | 规格:10 mg | 目录价:¥2626 |
| 货号:21509-25 mg | 规格:25 mg | 目录价:¥5856 |
| 货号:21509-5 mg | 规格:5 mg | 目录价:¥1447 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
NLG-919 analog
别名:
GDC-0919
产品描述:
An inhibitor of IDO1 and TDO (IC50s = 79 and 25 nM, respectively, in cell-free assays); decreases kynurenine levels in cells expressing human IDO1 (EC50 = 83 nM); decreases the percentage of PD-1+ anti-CD3- and anti-CD28-activated Jurkat T cells from 0.025-1 µM; decreases tumor volume and weight and the percentage of intratumoral CD4+CD25+ Tregs in a B16/F10 murine melanoma model at 100 mg/kg when administered alone or in combination with paclitaxel
保存温度:
-20
运输温度:
-20
预期分子量:
282.4
产品形式:
A crystalline solid
纯度:
≥98% (mixture of enantiomers)
CAS号:
1402836-58-1
分子式:
C18H22N2O
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