深圳欣博盛生物科技有限公司 a1

Norquetiapine
货号:36687-10 mg 规格:10 mg 目录价:¥1139
货号:36687-100 mg 规格:100 mg 目录价:¥9018.2
货号:36687-25 mg 规格:25 mg 目录价:¥2706.8
货号:36687-50 mg 规格:50 mg 目录价:¥4797.2
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Norquetiapine
别名:
N-Desalkylquetiapine
产品描述:
An active metabolite of quetiapine; selectively inhibits NET (IC50 = 12 nM) over SERT and DAT (IC50s = 988 and >10,000 nM, respectively); binds to the histamine H1 receptor (Ki = 3.5 nM), as well as 5-HT1, 5-HT2, and 5-HT7, α1- and α2-adrenergic, dopamine D1-D5, and M1-M5 muscarinic receptors (Kis = 45-1,117 nM, 95-736, 196-1,419, and 23-453 nM, respectively); an antagonist at histamine H1, α1A- and α1D-adrenergic, M1, M3, and M5 muscarinic receptors in a concentration-dependent manner and an agonist at the 5-HT1A receptor (EC50 = 4,898 nM); reduces increases in immobility time in Vmat2 heterozygous mice at 0.1, 0.5, and 1 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
295.4031
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
5747-48-8
分子式:
C17H17N3S
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