深圳欣博盛生物科技有限公司 a1

Notopterol
货号:39268-1 mg 规格:1 mg 目录价:¥375
货号:39268-10 mg 规格:10 mg 目录价:¥2412
货号:39268-5 mg 规格:5 mg 目录价:¥1568
货号:39268-50 mg 规格:50 mg 目录价:¥6459
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Notopterol
产品描述:
A furanocoumarin with diverse biological activities; a JAK2 and JAK3 inhibitor (IC50s = 9.51 and 25.2 µM, respectively); selective for JAK2 and JAK3 over TYK2 and JAK1 (IC50s = >667 and >2,000 µM, respectively); induces apoptosis and mitochondrial membrane depolarization in HL-60 cells at 40 and 60 µM; induces cell cycle arrest at the G0/G1 phase in HL-60 cells at 10, 20, and 40 µM; decreases acetic acid-induced writhing and vascular permeability in mice at 100 mg/kg; increases the duration of pentobarbital-induced sleep in mice at 10 or 30 mg/kg; reduces joint swelling, inhibits decreased talus bone volume, and reduces meniscus and talus osteoclast numbers in a mouse model of collagen-induced arthritis at 20 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
354.39638
产品形式:
A solid
纯度:
≥95%
来源:
Plant/Hansenia weberbaueriana
CAS号:
88206-46-6
分子式:
C21H22O5
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