| 货号:23872-1 mg | 规格:1 mg | 目录价:¥482 |
| 货号:23872-10 mg | 规格:10 mg | 目录价:¥3591 |
| 货号:23872-25 mg | 规格:25 mg | 目录价:¥7866 |
| 货号:23872-5 mg | 规格:5 mg | 目录价:¥2050 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
NS 11394
产品描述:
A positive allosteric modulator of the GABAA receptor (Ki = 0.423 nM); selective for GABAA receptors containing α1, α2, α3, or α5 subunits (Kis = 0.41, 0.84, 0.497, and 0.119 nM, respectively) over receptors containing α4 or α6 subunits (Kis = 324 or 1,009 nM, respectively); modulator of GABA receptors containing subunits α3 and α5 with maximal potentiation rates of 52% and 78%, respectively, relative to diazepam; inhibits [3H]flunitrazepam binding to benzodiazepine receptors in mouse and rat forebrain in vivo (EC50s = 0.38 and 1.3 mg/kg, respectively, at 30 minutes and 0.49 and 0.69 mg/kg, respectively, at 120 minutes following oral administration); attenuates spontaneous nociceptive behaviors in a rat model of neuropathic pain when administered at doses of 1-30 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
353.4
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
951650-22-9
分子式:
C23H19N3O
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