深圳欣博盛生物科技有限公司 a1

NS 8593 (hydrochloride)
货号:29774-1 mg 规格:1 mg 目录价:¥428.8
货号:29774-10 mg 规格:10 mg 目录价:¥2546
货号:29774-25 mg 规格:25 mg 目录价:¥5802.2
货号:29774-5 mg 规格:5 mg 目录价:¥1380.2
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
NS 8593 (hydrochloride)
产品描述:
An inhibitory gating modifier of SK channels (Kds = 0.42, 0.6, and 0.73 μM for SK1, SK2, and SK3, respectively, in the presence of calcium); decreases the calcium sensitivity of SK channels; selective for SK channels over IK and BK potassium channels at 10 μM; induces relaxation of potassium- or acetylcholine chloride-precontracted isolated tracheal rings from wild-type mice (IC50s = 8.9 and 39.8 μM, respectively) or from mice in an ovalbumin-induced model of allergic asthma (IC50s = 16.4 and 32.2 μM, respectively); inhibits aerosolized acetylcholine chloride-induced increases in respiratory system resistance in mice when administered as an aerosol at 500 μM; decreases the duration of burst-pacing-induced atrial fibrillation in normotensive and spontaneously hypertensive rats at 5 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
299.8
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
875755-24-1
分子式:
C17H17N3 • HCl
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