NUMB Antibody-多抗-深圳欣博盛生物科技有限公司

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NUMB Antibody

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：RQ8514

规格：100 ug

目录价：￥6488.05

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

NUMB Antibody

产品描述:

Protein numb homolog is a protein that in humans is encoded by the NUMB gene. It is mapped to 14q24.2 to q24.3. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. The primary function of Numb in cell differentiation is as an inhibitor of Notch signaling which is essential for maintaining self-renewal potential in stem and progenitor cells. Numb also plays a crucial role in asymmetrical cell division during development, allowing for differential cell fate specification in the central and peripheral nervous systems. Whatï¿½s more, the numb gene protein product controls binary cell fate decisions in the peripheral and central nervous systems of both invertebrates and mammals during neurogenesis.

反应种属:

Human, Monkey, Mouse, Rat

宿主来源:

Rabbit

实验应用:

WB, FACS, ELISA

同种型:

Rabbit IgG

免疫原:

An E.coli-derived human recombinant protein (amino acids E59-A567) was used as the immunogen for the NUMB antibody.

克隆性:

Polyclonal (rabbit origin)

纯化方式:

Antigen affinity purified

保存温度:

After reconstitution, the NUMB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

产品形式:

Antigen affinity purified

存储溶液:

0.5mg/ml if reconstituted with 0.2ml sterile DI water

产地:

美国

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