| 货号:13641-1 mg | 规格:1 mg | 目录价:¥1729 |
| 货号:13641-10 mg | 规格:10 mg | 目录价:¥11283 |
| 货号:13641-5 mg | 规格:5 mg | 目录价:¥6445 |
| 货号:13641-500 µg | 规格:500 µg | 目录价:¥1206 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
NVP-AEW541 (hydrochloride)
产品描述:
An IGF-1R inhibitor (IC50 = 0.15 µM in a cell-free assay); selective for IGF-1R over a panel of 20 kinases but also inhibits InsR, FLT1, FLT3, and Tie2 (IC50s = 0.14, 0.6, 0.42, and 0.53 µM, respectively, in cell-free assays); selectively inhibits the autophosphorylation of IGF-1R over InsR, EGFR, PDGFR, c-Kit, and Bcr-Abl in cells (IC50s = 0.086, 2.3, >10, >10, >5, and >10 µM, respectively); reduces tumor volume in an NWT-21 murine fibrosarcoma model at 20, 30, or 50 mg/kg twice per day
保存温度:
-20
运输温度:
-20
预期分子量:
439.58
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
2320261-63-8
分子式:
C27H29N5O • 2HCl
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