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折扣/货期| 货号：11587-10 mg | 规格：10 mg | 目录价：￥657 |
| 货号：11587-25 mg | 规格：25 mg | 目录价：￥1514 |
| 货号：11587-5 mg | 规格：5 mg | 目录价：￥389 |
| 货号：11587-50 mg | 规格：50 mg | 目录价：￥2090 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
NVP-BKM120
别名:
Buparlisib
产品描述:
An inhibitor of the class I PI3K isoforms p110α (IC50 = 52 nM) and p110β (IC50 = 166 nM); selective for these isoforms over the class III PI3K Vps34 (IC50 = 2,410 nM), mTOR (IC50 = 2,866 nM), PI4Kβ (IC50 = >25,000 nM), and a variety of kinases (IC50s = >10,000 nM); inhibits proliferation of human tumor and glioma cell lines, with p53 wild-type glioma cells more sensitive than p53 mutant/deleted glioma cells (IC50s = 1.28 and 2.08 µM, respectively); crosses the blood brain barrier; increases survival in a U87 glioma mouse xenograft intracranial tumor model when orally administered at 20 and 40 mg/kg once per week
保存温度:
-20
运输温度:
-20
预期分子量:
410.4
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
944396-07-0
分子式:
C18H21F3N6O2
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