| 货号:25643-1 mg | 规格:1 mg | 目录价:¥616 |
| 货号:25643-10 mg | 规格:10 mg | 目录价:¥4494 |
| 货号:25643-25 mg | 规格:25 mg | 目录价:¥9688 |
| 货号:25643-5 mg | 规格:5 mg | 目录价:¥2408 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
ODM-201
别名:
BAY 1841788
产品描述:
An androgen receptor antagonist (Ki = 11 nM); inhibits AR transactivation in U2OS osteosarcoma cells expressing human wild-type and mutant ARs (IC50s = 65, 66, 1,500, and 1,782 nM for wild-type, ARF876L, ARW741L, and ART877A, respectively); prevents androgen-induced AR nuclear translocation in AR-overexpressing HS-HEK293 and LNCaP cells; suppresses androgen-induced proliferation of VCaP cells (IC50 = 230 nM); reduces tumor growth in a VCaP castrated mouse xenograft model at 50 mg/kg per day; inhibits tumor growth without increasing serum testosterone levels in a VCaP intact mouse xenograft model
保存温度:
-20
运输温度:
-20
预期分子量:
398.9
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
1297538-32-9
分子式:
C19H19ClN6O2
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