Olr1 Antibody / Lox-1-多抗-深圳欣博盛生物科技有限公司

首页产品中心多抗

Olr1 Antibody / Lox-1

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：RQ6063

规格：100 ug

目录价：￥6488.05

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Olr1 Antibody / Lox-1

产品描述:

OLR1 (oxidized low density lipoprotein (lectin-like) receptor 1) also called CLEC8A, LOX-1, SCARE1, is a receptor protein which belongs to the C-type lectin superfamily. The OLR1 gene encodes a cell-surface endocytosis receptor for oxidized low density lipoprotein (OxLDL). This gene is mapped on 12p13.2. Incubation of the cells with LDL had no effect on LOX1 expression, but incubation with OxLDL resulted in a dose-dependent increase in LOX1 mRNA and protein expression; however, very high concentrations of OxLDL caused a decrease in OxLDL expression, perhaps indicating toxic effects on endothelial cells. LOX1 was also expressed in macrophages, but not in vascular smooth muscle cells. The findings suggested a role for LOX1 in the pathophysiology of atherosclerotic cardiovascular disease. LOX1 expression was detected in all choroidal neovascular membranes, regardless of structure, whereas there was no evidence of LOX1 within the posterior segments of normal eyes. LOX1 plays an active role in the pathogenesis of choroidal neovascularization, especially in ARMD.

反应种属:

Mouse

宿主来源:

Rabbit

实验应用:

WB, Direct ELISA

同种型:

Rabbit IgG

免疫原:

Recombinant mouse protein (amino acids Q55-I363) was used as the immunogen for the Olr1 antibody.

克隆性:

Polyclonal (rabbit origin)

纯化方式:

Affinity purified

保存温度:

After reconstitution, the Olr1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

产品形式:

Antigen affinity purified

存储溶液:

0.5mg/ml if reconstituted with 0.2ml sterile DI water

产地:

美国

您可能感兴趣的产品

Lyve-1 (human) antibody

货号：RLT-102-PABI50

Anti-Collagenase (Clostridium histolyticum), polyclonal antibody from sheep

货号：NB-58050-01

Anti-Collagenase (Clostridium histolyticum) HRP, polyclonal antibody from sheep