官网链接
折扣/货期| 货号：30370-1 mg | 规格：1 mg | 目录价：￥925 |
| 货号：30370-10 mg | 规格：10 mg | 目录价：￥5347 |
| 货号：30370-5 mg | 规格：5 mg | 目录价：￥3524 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Olutasidenib
别名:
FT-2102
产品描述:
An inhibitor of mutant IDH1 (IC50s = 0.021 and 0.114 µM for IDH1R132H and IDH1R132C, respectively); selective for mutant IDH1 over wild-type IDH1 and mutant IDH2 (IC50s = 22.4, 27.3, and >100 μM for wild-type IDH1, IDH2R172K, and IDH2R140Q, respectively); inhibits production of 2-HG in U87 cells expressing mutant IDH1R132H, IDH1R132C, IDH1R132L, IDH1R132G, and IDH1R132S (IC50s = 0.009, 0.039, 0.042, 0.006, and 0.009 µM, respectively); reduces intratumor 2-HG levels in HCT116-IDH1R132H and HCT116-IDH1R132C mouse xenograft models at 12.5, 25, and 50 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
354.79016
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1887014-12-1
分子式:
C18H15ClN4O2
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